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About

Who We Are

Engineering natural antimicrobial solutions

Selenium, Ltd. is a technology company specializing in the prevention of bacterial biofilm formation using molecular additives of redox active selenium for medical, dental, ophthalmic and industrial applications. Our Seldox™ technology addresses the needs of many biomedical and industrial companies for an effective, low cost, and safe antibiofilm coated or integrated technology.

Selenium Ltd.'s proprietary technology is able to inhibit bacterial biofilm formation and attachment on surfaces through a covalently linked, catalytic, and safe compound that does not leach into the surrounding environment. These properties allow for protection against biofilm for the duration of the useful life of the substrate.

Hospital Acquired Infections (HAI) Numbers

4%

of Patients get a HAI

0

HAI infections per year

$33.8

Billion to treat HAI per year

75k

Deaths per Year

Technology

Applications

Medical Devices

Seldox compounds can protect surfaces by acting as an impenetrable barrier to microbes and other cellular growths.

Industrial applications

For industrial applications, Selenium has unique benefits over existing technologies: Selenium can be covalently attached to a surface.

Therapeutic Drug Arming

Selenium compounds may be used as an arming agent for antibodies, peptides, small molecules, and nucleotides.

Selenium has an extensive intellectual property portfolio including foreign and U.S. Patents.

About Our Anti-Biofilm Technology

Based on redox chemistry, Seldox compounds create a flux of superoxide radicals. These superoxide radicals can affect biofilm growth by altering protein folding needed to initiate a biofilm, inhibiting needed respiratory and metabolic functions, causing minor membrane lesions, and even leading to the development of longer lasting radicals. This process mimics the body's own defense against bacteria. White blood cells, leukocytes, can produce superoxide radicals in order to destroy bacteria during phagocytosis.

Seldox compounds enable focused inhibition while not harming bystander cells. The half-life of the superoxide radicals limits the effective zone to approximately 350 angstroms. This short active range makes the technology ideal for the prevention of biofilm formation. In addition, natural mammalian cell defenses to oxidative stress are sufficient to deal with dilute superoxide concentrations, making it safe for medical applications.



 

Industry Validation and National Recognition

"Selenium received a $140,000 Small Business Technology Transfer (STTR) grant for research and development of antimicrobial dental water lines."

"Selenium, Ltd. received a National Institutes of Health (NIH) two-year $912,943 grant to develop antimicrobial dental devices and water lines."

"Selenium recieved a $500,000 Small Business Innovation Research (SBIR) grant for research and development of antimicrobial reverse osmosis spacers."

Interested in Partnership Oppportunities? Get in Touch

Contact

Get In Touch

We would love to hear from you!

(512) 697-8219

7500 Rialto Blvd., Bldg 2 Ste. 260 Austin, TX 78735

info@selenbio.com

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